| ENZ-ABS741-0100 | 100 µl | 445.00 USD |  |
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| Alternative Name: | Six transmembrane epithelial antigen of the prostate 1, Metalloreductase STEAP1 |
| Clone: | J2D2 |
| Host: | Mouse |
| Isotype: | IgG2bκ |
| Immunogen: | Recombinant human STEAP1 (aa 1-70) purified from E. coli. |
| UniProt ID: | Q9UHE8 |
| Source: | Purified from ascites. |
| Species reactivity: | Human |
| Applications: | ELISA, ICC, IF, IHC, WB |
| Recommended Dilutions/Conditions: | Western Blot (1:1,000). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Protein G affinity purified |
| Formulation: | Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Six-transmembrane epithelial antigen of the prostate (STEAP) is expressed predominantly in human prostate tissue and in other common malignancies including prostate, bladder, colon, and ovarian carcinomas, and in Ewing's sarcoma, suggesting that it could function as an almost universal tumor antigen. Immunohistochemical analysis indicated STEAP-1 localization at cell-cell junctions of the secretory epithelium of prostate and prostate cancer cells. The favorable expression profiling of STEAP-1 in normal and cancer tissues suggested its potential use as a target for immunotherapy. |
| Regulatory Status: | RUO - Research Use Only |
