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STEAP1 monoclonal antibody (J2D2)

 
ENZ-ABS741-0100 100 µl 355.00 USD
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Product Specification

Alternative Name:Six transmembrane epithelial antigen of the prostate 1, Metalloreductase STEAP1
 
Clone:J2D2
 
Host:Mouse
 
Isotype:IgG2bκ
 
Immunogen:Recombinant human STEAP1 (aa 1-70) purified from E. coli.
 
UniProt ID:Q9UHE8
 
Source:Purified from ascites.
 
Species reactivity:Human
 
Applications:ELISA, ICC, IF, IHC, WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000).
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified
 
Formulation:Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Six-transmembrane epithelial antigen of the prostate (STEAP) is expressed predominantly in human prostate tissue and in other common malignancies including prostate, bladder, colon, and ovarian carcinomas, and in Ewing's sarcoma, suggesting that it could function as an almost universal tumor antigen. Immunohistochemical analysis indicated STEAP-1 localization at cell-cell junctions of the secretory epithelium of prostate and prostate cancer cells. The favorable expression profiling of STEAP-1 in normal and cancer tissues suggested its potential use as a target for immunotherapy.
 

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