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B7-H3 monoclonal antibody (2A7)

 
ENZ-ABS701-0100 100 µg 457.00 USD
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Product Specification

Alternative Name:CD276,
 
Clone:2A7
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Extracellular domain of human B7-H3.
 
UniProt ID:Q5ZPR3
 
Species reactivity:Human
 
Applications:Flow Cytometry, ICC, IF, IHC (PS), WB
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:CD276 was initially identified as a member of the B7 family of proteins. CD276 mRNA is widely expressed, but its protein expression is usually rather low. CD276 has been shown to play a role in both the costimulation as well as the coinhibition of T cell response. CD276 also plays a critical role in the control of antitumor immune responses in some cases, while in others appears to mediate antitumor immunity. It is a possible therapeutic target for at least a subset of cancers.
 

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