UbcH7 (human), (recombinant) (His-tag)

MW:	18 kDa

Source/Host:	Produced in E. coli.

Long Term Storage:	-80°C

Miscellaneous/General:	UbcH7 is a class I enzyme which functions in the stress response and the control of transcription factors1. The enzyme is ubiquitously expressed with high levels of expression seen in adult muscle2. It has been demonstrated to participate in the ubiquitinylation of p53, c-Fos and NF-κB. UbcH7 is one of two E2s (UbcH5 being the other) with which HECT domain proteins interact with UbcH7 being able to efficiently substitute for UbcH5 in E6-AP-dependent ubiquitinylation.

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