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PDE4A (catalytic domain) (human), (recombinant)

 
BML-SE521-0020 20 µg 459.00 USD
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Product Specification

Alternative Name:Phosphodiesterase 4A
 
MW:37 kDa
 
Source:Produced in E. coli. Active catalytic domain of phosphodiesterase 4A.
 
UniProt ID:P27815
 
Formulation:Liquid. In 20mM Tris-HCl, pH 8.0, containing 150mM NaCl, 2mM DTT.
 
Application Notes:Useful for kinetic and functional studies, phosphorylation of target substrates, drug screening.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Scientific Background:PDE4A is the primary cAMP metabolizing enzyme and is expressed in many inflammatory cells. Its inhibition attenuates the production of various inflammatory cell functions. It is inhibited by rolipram.
 

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