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Z-Leu-Leu-CHO

Calpain inhibitor
 
BML-PI116-0005 5 mg 77.00 USD
 
BML-PI116-0025 25 mg 317.00 USD
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Selective inhibitor of calpain, 100-fold selective for calpain over proteasome.

Product Specification

Sequence:Z-Leu-Leu-CHO
 
MW:362.5
 
Source:Synthetic.
 
Purity:≥98% (TLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in DMSO or ethanol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C or colder for up to 1 year. Store solutions at –20°C or colder for up to 3 months.
 
BML-PI116 structure
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BML-PI116 structure

Product Literature References

Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin: T.L. Campbell, et al.; Data Brief 7, 786 (2016), Application(s): Measured calpain activity in mixed gastrocnemius homogenates, Abstract;
Differential apoptosis-related protein expression, mitochondrial properties, proteolytic enzyme activity, and DNA fragmentation between skeletal muscles: E.M. McMillan, et al.; Am. J. Physiol. Regul. Integr. Comp. Physiol. 300, R531 (2011), Abstract; Full Text

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