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MMP substrate α (fluorogenic)

 
BML-P131-0001 1 mg 114.00 USD
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Fluorogenic substrate for several matrix metalloproteinases (MMPs). It is cleaved by MMP-1 (kcat/Km=3.3x10M-1s-1), MMP-2 (kcat/Km=5.8x10), MMP-3 (kcat/Km=2.2x10), MMP-7 (kcat/Km=1.2x10), MMP-8, MMP-9 (kcat/Km=6.9x10), and MMP-26 (kcat/Km=4.9x10) Ex/Em=280nm/346nm, although 283/350,360 are also appropriate. Fluorescence at 346 nm by tryptophan occurs once cleavage separates it from the quenching aromatic Dnp moiety. MMPs cleave this peptide between Gly-Leu.

Product Specification

Alternative Name:Matrix metalloproteinase substrate α
 
Sequence:Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 (Dnp=2,4-dinitrophenyl)
 
Formula:C45H64N14O11
 
MW:977.09
 
CAS:121282-17-5
 
Purity:≥94% (HPLC)
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 

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