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24(S),25-Epoxycholesterol

LXR ligand
 
BML-GR231-0001 1 mg 204.00 USD
 
BML-GR231-0005 5 mg 905.00 USD
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Endogenous agonist for the nuclear receptor LXR.

Product Specification

Formula:C27H44O2
 
MW:400.6
 
CAS:77058-74-3
 
Purity:≥98% (TLC)
 
Identity:Determined by NMR.
 
Appearance:White solid.
 
MeltingPoint:156-159°C
 
Solubility:Soluble in ethanol (10mg/ml) or DMSO (10mg/ml - requires warming to ~40°C which has been shown to lead to significant decomposition of the product).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Product should be used immediately following dissolution.
 
Handling:Store with desiccant. Product packaged under inert gas.
 
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Product Literature References

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation: J.M. Carthy, et al.; Sci. Rep. 6, 29868 (2016), Application(s): Screening of chemical compounds with HaCaT cells, Abstract; Full Text
Nuclear receptors and lipid physiology: opening the X-files: A. Chawla, et al.; Science 294, 1866 (2001), Abstract;

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