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Buthionine sulfoximine

γ-Glutamyl transpeptidase inhibitor
 
BML-FR117-0500 500 mg 162.00 USD
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L-Buthionine-sulfoximine (BSO) induces oxidative stress in cells by irreversibly inhibiting γ-glutamylcysteine synthetase, an essential enzyme for the synthesis of glutathione.

Product Specification

Alternative Name:BSO
 
Formula:C8H18N2O3S
 
MW:222.3,
 
CAS:83730-53-4
 
Purity:≥97% (TLC)
 
Appearance:White solid.
 
Solubility:Soluble in water.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
BML-FR117 structure
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BML-FR117 structure

Product Literature References

A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C. elegans: B.A. Martinez, et al.; Cell Death Dis. 6, e1908 (2015), Application(s): Cell Culture, Abstract; Full Text
Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice: R. H. Schiestl & R. Reliene; Carcinogenesis 27, 240 (2006), Abstract;

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