A selective dopamine autoreceptor antagonist. Antagonizes the pharmacological effects of cocaine.
Product Details
| Formula: | C15H23NO . HCl |
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| MW: | 269.8 |
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| CAS: | 85379-09-5 |
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| Purity: | ≥98% (HPLC) |
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| Identity: | Determined by 1H-NMR. |
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| Appearance: | White crystalline solid. |
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| Solubility: | Soluble in 50% ethanol (20mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Store, a supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Intracerebral infusion of (+)-AJ76 and (+)-UH232: effects on dopamine release and metabolism in vivo: N. Waters et al.; Eur. J. Pharmacol.
251, 181 (1994),
Abstract;
Antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-AJ76 and (+)-UH232: M.F. Percy et al.; Brain Res.
588, 217 (1992),
Abstract;
(1S,2R)-5-methoxy-1-methyl-2-(n-propylamino)tetralin ([+]-AJ-76) elevates transmitter synthesis in dopaminergic neurons surviving a partial nigrostriatal lesion: F. Hefti ; Neuropharmacology
26, 1239 (1987),
Abstract;
