Bioactive lipid library



BML-2800-0500	1 Library	500 µl/well	INQUIRE

BML-2800-0100	1 Library	100 µl/well	INQUIRE

The Screen-Well™ Bioactive Lipid Library contains 195 bioactive lipids in a 96 well format. Ideal for screening or identifiying recombinant orphan G protein-coupled receptors, target validation, secondary screening, validating new assays and for routine pharmacological applications.

Product Specification

Quantity:	100 or 500µl per well.

Concentration:	DMSO solutions (1.0 or 0.1mM, depending on compound).

Long Term Storage:	-80°C

Kit/Set Contains:	195 compounds including: Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, HETEs deHETEs, hepoxilins, Polyunsaturated fatty acids, Leukotrienes, lipoxins, LPA & phosphatidic acids, Octadecanoids, PAFs, Prostaglandins & thromboxanes, Retinoids, vitamin D metabolites, Sphingolipids.

Background / Technical Information:

Product Literature References

Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress: I. Martins et al.; Oncogene 30, 1147 (2011), Application, Abstract;

Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay: H. Yin, et al.; J. Biol. Chem. 284, 12328 (2009), Abstract;

A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators: P. Stoilov et al.; Proc. Natl. Acad. Sci. USA 105, 11218 (2008), Application, Abstract;

Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18: M. Kohno, et al.; BBRC 347, 827 (2006), Abstract;

A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands: E. Kostenis et al.; Pharmacol. Ther. 102, 243 (2004), Abstract;

Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family: K. Noguchi et al.; J. Biol. Chem. 278, 25600 (2003), Abstract;