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RIP2 (human) monoclonal antibody (Nick-1)

 
ALX-804-139-C100 100 µg 356.00 USD
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Product Specification

Alternative Name:RICK, CARDIAK, CARD-containing interleukin-1β converting enzyme associated kinase, RIPK2, Receptor-interacting serine/threonine protein kinase 2, Receptor-interacting protein 2
 
Clone:Nick-1
 
Host:Rat
 
Isotype:IgG2a
 
Immunogen:Recombinant human RIP2 (receptor-interacting protein 2) (aa 1-322).
 
UniProt ID:O43353
 
Species reactivity:Human
 
Applications:WB
 
Positive Control:For Positive Control (Western blot) see Prod. No. ALX-840-604.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
804-139
Figure: Detection of endogenous human RIP2 in different human cell lines by the MAb to RIP2 (Nick-1) (Prod. No. ALX-804-139). Method: Total cell extracts (50µg) from Jurkat (lane1), THP-1 (lane 2) and HT1080 (lane 3) cell ljnes were run on a SDS-gel, and revealed with MAb to RIP2 (Nick-1) (1:1’000 in 5% milk powder) for 1 hour at rooom temperature followed by incubation with HRP-coupled anti-rat secondary antibody (1:4’000).
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804-139

Product Literature References

BNN-20, a synthetic microneurotrophin, strongly protectsdopaminergic neurons in the "weaver" mouse, a genetic model of dopamine-denervation, acting through the TrkB neurotrophin receptor: K. Botsakis, et al.; Neuropharmacology 121, 140 (2017), Abstract;
Participation of Rip2 in lipopolysaccharide signaling is independent of its kinase activity: C. Lu, et al.; J. Biol. Chem. 280, 16278 (2005), Abstract; Full Text
Participation of Rip2 in LPS signaling is independent of its kinase activity: C. Lu, et al.; J. Biol. Chem. 280, 16278 (2005), Abstract; Full Text
PIDD mediates NF-kB activation in Response to DNA damage: Janssens, et al.; Cell 123, 1079 (2005), Abstract;

Related Products

Positive control (cell lysate), for antibodies to RIP2 (human) 

Whole cell lysate of HEK 293T cells transfected with an expression plasmid for human RIP2 (receptor-interacting protein 2) (aa 1-541) fused at the C-terminus to a FLAG®-tag. | Print as PDF
 
ALX-840-604-R100 100 µl 49.00 USD
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