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(+)-Bicuculline

GABAA receptor antagonist
 
ALX-550-515-M050 50 mg 53.00 USD
 
ALX-550-515-M250 250 mg 197.00 USD
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GABAA receptor antagonist.

Product Specification

Alternative Name:D-Bicuculline
 
Formula:C20H17NO6
 
MW:367.4
 
CAS:485-49-4
 
MI:14: 1203
 
RTECS:LV0909840
 
Purity:≥98% (HPLC)
 
Appearance:Off-white to yellow powder.
 
Solubility:Soluble in benzene, chloroform or ethyl acetate.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
550-515
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Product Literature References

Nuclear calcium signaling induces expression of the synaptic organizers lrrtm1 and lrrtm2: S.N. Hayer, et al.; J. Biol. Chem. 290, 5523 (2015), Application(s): Cell Culture, Abstract; Full Text
Synaptic NMDA Receptor Activation Stimulates α-Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-β Production: Sarah E. Hoey, et al.; J. Neurosci. 29, 4442 (2009), Abstract;
Convulsant bicuculline modifies CNS muscarinic receptor affinity: P.G. Schneider and G. Rodriguez de Lores Arnaiz; BMC Neurosci. 7, 32 (2006), Abstract; Full Text
Cannabinoid suppressed bicuculline-induced convulsion without respiratory depression in the brainstem-spinal cord preparation from newborn rats: S. Koda, et al.; Biomed. Res. 26, 241 (2005), Abstract; Full Text

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