Selective and cell permeable inhibitor of G9a histone methyltransferase.
Product Specification
| Alternative Name: | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]4-quinazolinamine |
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| Identity: | Identity determined by MS, 1H- and 13C-NMR. |
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| Formula: | C28H38N6O2 |
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| MW: | 490.6 |
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| Purity: | ≥95% |
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| Appearance: | Light brown to brown solid. |
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| CAS: | 935693-62-2 |
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| Solubility: | Soluble in DMSO (5mg/ml). |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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Product Literature References
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase: S. Kubicek, et al.; Mol. Cell
25, 473 (2007),
Abstract;