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Ac-LEVD-AMC

Caspase-4 substrate
 
ALX-260-083-M001 1 mg 57.00 USD
 
ALX-260-083-M005 5 mg 126.00 USD
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Fluorogenic substrate for caspase-4.

Product Specification

Alternative Name:Caspase-4 substrate (fluorogenic)
 
Sequence:Ac-Leu-Glu-Val-Asp-AMC (AMC=7-Amino-4-methylcoumarin)
 
Formula:C32H43N5O11
 
MW:673.7
 
Peptide Content:75-95%
 
Purity:≥99% (HPLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in DMSO. Dilute with distilled water or buffer, pH 7.5.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Keep cool and dry.
 
Technical Info/Product Notes:AMC has an excitation maximum of 340-360nm and an emission maximum of 440-460nm.
 

Product Literature References

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis: N.A. Thornberry, et al.; J. Biol. Chem. 272, 17907 (1997), Abstract; Full Text

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