Product Details
| Alternative Name: | X-ray repair cross-complementing group 1 |
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| Host: | Rabbit |
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| Immunogen: | Recombinant human XRCC1 (X-ray repair cross-complementing group 1) fused to a His-tag. |
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| UniProt ID: | P18887 |
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| Species reactivity: | Human
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| Applications: | ICC, IP, WB
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| Recommended Dilutions/Conditions: | Immunocytochemistry (1:1,000)
Immunoprecipitation (1:200)
Western Blot (1:2,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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| Formulation: | Liquid. Antiserum containing 0.1% sodium azide. |
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| Use/Stability: | Stable for at least one year when stored at +4°C. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Figure 1: Western blot analysis of endogenous and recombinant XRCC1 using PAb to XRCC1 (human) (Prod. No.
ALX-210-539). Lane 1: HeLa cells. Lane 2: Recombinant human XRCC1 (10ng)."
Figure 2: Immunoprecipitation of endogenous XRCC1 from HeLa cells. Lane 1: PAb to XRCC1 (human) (Prod. No.
ALX-210-304) (5µl). Lane 2: PAb to XRCC1 (human) (Prod. No.
ALX-210-304) (10µl). Lane 3: PAb to XRCC1 (human) (Prod. No.
ALX-210-539) (5µl). Lane 4: PAb to XRCC1 (human) (Prod. No.
ALX-210-539) (10µl). Lane 5: Pre-immune serum."
Figure 3: Immunocytochemistry of endogenous XRCC1 in HeLa cells using PAb to XRCC1 (human) (Prod. No.
ALX-210-539) (1:1’000)."
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Product Literature References
Radiation-induced mitotic catastrophe in PARG-deficient cells: JC. Amé, et al.; J. Cell Sci.
122, 1990 (2009),
Abstract;
XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage: N. Levy, et al.; Nucl. Acids Res.
34, 32 (2006),
Abstract;
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XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage: M. Masson, et al.; Mol. Cell. Biol.
18, 3563 (1998),
Abstract;
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