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[pSer10]Histone H3 polyclonal antibody

 
ADI-905-780-100 100 µg 269.00 USD
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Product Specification

Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to human Histone H3 phosphorylated at Ser10.
 
UniProt ID:P68431 (Histone H3.1), Q71DI3 (Histone H3.2), P84243 (Histone H3.2)
 
Species reactivity:Human
 
Crossreactivity:Weakly cross-reacts with mouse, rat, chicken, Drosophila, monkey, pig and rabbit Histone H3.
 
Applications:WB
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The core histones form an octamer, which is made up of one H3-H4 tetramer and two H2A-H2B dimers. The N-terminal tail of core histones undergoes different post-transcriptional modifications including acetylation, phosphorylation, methylation and ubiquitination. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression.
 
905-780 WB
Western blot analysis of MW marker (1), untreated Jurkat (2), and calyculin A-treated Jurkat (3) cell lysates probed with Histone H3 (pSer10) pAb.
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905-780 WB

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