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Webinars - Clinical

Passed Webinars

The value of in situ detection of SARS-CoV-2 RNA and proteins in understanding the pathophysiology of severe COVID-19

Understanding the histopathology of COVID-19 has proven to be a major gateway to understanding the molecular mechanisms through which SARS-CoV-2 manifests disease. The group of Dr. Nuovo has contributed significantly to understanding the pathophysiology of severe COVID-19 and utilized Enzo’s AMPIVIEW SARS-CoV-2 RNA probes kit in the process. He will present the highlights of his group’s findings in Enzo’s webinar series. Amongst them: 1. Detection of SARS-CoV-2 RNA in situ shows that productive infection predominates in the nasopharynx and lung; 2. Detection of SARS-CoV-2 proteins (nucleocapsid, spike, envelope and matrix) show that spike is avidly endocytosed via the vascular system in several sites, including the brain and heart; viral RNA is rarely evident in these sites; 3. Correlation of the host response to the in situ localization of SARS-CoV-2 RNA and spike protein shows that each are associated with increased expression of proinflammatory proteins including TNFa and IL6 as well as complement activation.

Main Target Audience: Pathophysiologists; Clinical Laboratories; Hospitals; Histologists; Virologists - Researchers interested in the following topics: Coronavirus, in situ Hybridization (ISH); Antibodies; Clinical Diagnostics; DNA/Protein Labeling, HPV, Immunohistochemistry (IHC), Immunology, Inflammation, Pathology, Virology.

Why should you attend?: Whether you are a scientist, a student, a lab technician, or a curious citizen, this webinar will provide fascinating mechanistic insight into the pathophysiology of severe COVID-19, while simultaneously providing a wealth of practical knowledge on the laboratory technologies utilized in detecting viral RNA and proteins, especially in situ hybridisation and immunohistochemistry.

Presented by: Dr. Gerard J. Nuovo
Professor of Pathology
Ohio State University Comprehensive Cancer Center

Topic: Clinical



How to increase laboratory-based COVID-19 testing capacity

The COVID-19 pandemic is still a big threat for the United States. Diagnostic testing is critical to monitor and contain the disease; however, the increasing testing demand has created a shortage in laboratory-based molecular tests. In this webinar, we highlight the challenges faced by clinical laboratories in ramping up their testing capacity and provide potential solutions. Additionally, we discuss a case study on Enzo Clinical Labs and its ability in managing the COVID-19 clinical testing demand during the outbreak in New York.

Presented by: Albino Troilo
PhD, Sr. Marketing Manager at Enzo
Enzo

Topic: Clinical



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