Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Macropinocytosis – when cells are just gulping it down

Hartmut Pohl
Tags: Infographic


Recently macropinocytosis has gotten a lot of attention for its varied functions in nutrition absorption, immunological surveillance, viral and cancer pathologies. Macropinocytosis is one of the central mechanisms by which cells take up extracellular materials. Macropinocytosis allows cells to eat and drink by ingesting both fluid and nutrients from the external milieu.

Fast Facts:
  • Macropinocytosis is a signal-dependent process that occurs in most cells upon stimulation with a growth factor (e.g., CSF-1, EGF, PDGF) or tumor-promoting factor (e.g., PMA).
  • Macrophages and dendritic cells use constitutively macropinocytosis to sample their environment for antigens.
  • Certain viruses and bacteria exploit macropinocytosis to enter host cells and spread infection.

Please take a look at our latest infographic on micropinocytosis and see Enzo’s solutions (cell viability, cytotoxicity assay, calcium mobilization, ROS detection, compound libraries for neuromodulator screening) to study macropinocytosis in physiology, disease, and therapy.

Contact our application scientists today.
 

Download the infographic

Did you enjoy the reading?
Share it on your favorite social media

 
comments powered by Disqus

Never miss a new TechNote!

Receive our TechNotes as soon as they are published.


Follow Us!

 

Recommend this page

 
Keep in touch

©2022 Enzo Life Sciences, Inc.,