Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Quantification of Stress in Space

Astronauts face various physiological and biological challenges after their descent into the cosmos including space motion sickness, bone demineralization, fatigue, and even isolation. Space physiology studies are limited due to minimal access to astronauts. Today’s technology, however, has allowed us to extract information even from small sample sizes. Blood biomarkers, anti-inflammatory cytokines, and more are easily measured and studied using ELISA kits, available through Enzo Life Sciences.

Stem Cells
In a recent study, researchers evaluated the pro/anti-inflammatory state of two crewmembers spending six months in space. C-proteasome quantification was conducted on the astronauts, both of same sex and similar age using our Proteasome 20S α1, 2, 3, 5, 6 & 7 subunits mAb (MCP231). Proteasomes degrade unnecessary proteins by breaking peptide bonds via proteases. By quantifying these protein complexes, researchers are able to evaluate overall health, or lack thereof. At the end of the study, c-proteasome amounts were significantly higher in both subjects, indicating disease activity and an autoimmune response. Such results are consistent with the prolonged stress of spaceflight, and the inflammation that follows. Sound too sci-fi to be true? It’s not! Increased c-proteasome indicated a tissue injury, which can be compared to levels present in patients of autoimmune diseases, indicating muscle wasting.

Enzo Life Sciences provides a range of products for all your Immunology and Metabolism research needs. Our platform provides a wide range of assay kits, small molecules, antibodies, and proteins. We offer activating enzymes (E1s), conjugating enzymes (E2s), ligases (E3s) and deconjugating enzymes (DCEs), plus an innovative range of ubiquitin-, SUMO-, NEDD8-, ISG15- and FAT10-associated proteins and derivatives. Discover ubiquitin- and Ubl-reactive antibodies, kits for the study of ubiquitin, SUMO, and NEDD8 conjugation, and our easy-to-use UBIQAPTURE-Q® and SUMO-QAPTURE-T® kits for the detection and isolation of ubiquitinated and SUMOylated proteins.

Tags: In The News

Never miss a new TechNote!

Receive our TechNotes as soon as they are published.

comments powered by Disqus

Follow Us!


Related Products

Proteasome 20S α1, 2, 3, 5, 6 & 7 subunits monoclonal antibody (MCP231) 

Purified from ascites., IHC, WB | Print as PDF
BML-PW8195-0025 25 µl 143.00 USD
BML-PW8195-0100 100 µl 466.00 USD
Do you need bulk/larger quantities?


The only commercially available kit for isolation and enrichment of SUMOylated proteins.
Print as PDF
BML-UW1000A-0001 10 tests 468.00 USD
Do you need bulk/larger quantities?

Ubiquitinylation kit 

Versatile tool for generation of ubiquitin-E2 thioesters.
Print as PDF
BML-UW9920-0001 1 Kit 661.00 USD
Do you need bulk/larger quantities?

Auto-ubiquitinylation kit 

Well-validated test to assess ubiquitin E3 ligase activity
Print as PDF
BML-UW0970-0001 10 tests 320.00 USD
Do you need bulk/larger quantities?

NEDDylation Kit 

Print as PDF
BML-UW0590-0001 20 tests 482.00 USD
Do you need bulk/larger quantities?

Ubiquitin activating kit 

Print as PDF
BML-UW0400A-0001 20 tests 218.00 USD
Do you need bulk/larger quantities?

SUMO activating enzyme E1 (human), (recombinant) 

Produced in E. coli. Full length heterodimeric human SUMO-activating enzyme. | Print as PDF
BML-UW9330-0025 25 µg 344.00 USD
Do you need bulk/larger quantities?

SUMO-1 (human) (CT) polyclonal antibody 

Purified from rabbit serum., WB | Print as PDF
BML-PW9460-0025 25 µl 142.00 USD
BML-PW9460-0100 100 µl 481.00 USD
Do you need bulk/larger quantities?

ISG15 (human), (recombinant) (His-tag) 

Produced in E. coli., ≥95% (SDS-PAGE) | Print as PDF
BML-UW9235-0500 500 µg 252.00 USD
Do you need bulk/larger quantities?

NEDD8 (human), (recombinant) (His-tag) 

Produced in E. coli. Human NEDD8 is fused with the N-terminal His-tag., ≥95% (SDS-PAGE) | Print as PDF
BML-UW9225-0500 500 µg Inquire for pricing
Do you need bulk/larger quantities?

Recommend this page