Elephants have surprisingly low rates of cancer for their large size and long lives. Understanding how these animals have lower cancer rates may provide essential information for developing cancer treatments. Humans have one copy of the well-studied anticancer gene, p53, which can sense damaged DNA. Interestingly, elephants have 20 copies of the p53 gene that respond to DNA damage by switching on a unique gene that destroys cells instead of repairing the cell.
Tags: Cancer, In the News
Receive our TechNotes as soon as they are published.
GFP-CERTIFIED® Apoptosis/Necrosis detection kit |
||||||
| Multiplex assay that distinguishes between healthy, early apoptotic, late apoptotic and necrotic cells, compatible with GFP and other fluorescent probes (blue or cyan) | ||||||
| Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF | ||||||
| ENZ-51002-25 | 25 assays | 204.00 USD |  |
|||
| ENZ-51002-100 | 100 assays | 476.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
LIF (mouse), (recombinant) |
||||||
| Produced in E. coli., ≥95% (SDS-PAGE) | Print as PDF | ||||||
| ALX-201-242-L001 | 1 ml | 1,475.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
Bax (human) (58-75), (cell permeable) |
||||||
| ≥95% (HPLC) | Print as PDF | ||||||
| ALX-152-028-1 | 1 Vial | 271.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
Etoposide |
||||||
| Topoisomerase inhibitor. p53 activator. | ||||||
| 33419-42-0, Semisynthetic derivative of podophyllotoxin., ≥95% (HPLC) | Print as PDF | ||||||
| BML-GR307-0100 | 100 mg | 114.00 USD | |
|||
| BML-GR307-0500 | 500 mg | 462.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
CP-31398 |
||||||
| p53 activator | ||||||
| 259199-65-0, Synthetic., ≥98% (HPLC) | Print as PDF | ||||||
| BML-GR360-0010 | 10 mg | 145.00 USD | |
|||
| BML-GR360-0050 | 50 mg | 593.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
p53 (wild type) (human), (recombinant) |
||||||
| Produced in E. coli., ≥90% (SDS-PAGE), ELISA, WB, Inhibition assay | Print as PDF | ||||||
| ADI-908-265-010 | 10 µg | 609.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
p53 Recombinant monoclonal antibody (PAb421) (Mouse IgG2aκ) |
||||||
| ELISA, IF, IHC (FS), IHC (PS), IP, WB | Print as PDF | ||||||
| ENZ-ABS653-0200 | 200 µg | 580.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
(S)-(+)-Camptothecin |
||||||
| Potent antitumor agent | ||||||
| 7689-03-4, Isolated from Camptotheca acuminata seeds., ≥98% (HPLC) | Print as PDF | ||||||
| ALX-350-015-M050 | 50 mg | 67.00 USD | |
|||
| ALX-350-015-M250 | 250 mg | 239.00 USD | |
|||
| ALX-350-015-G001 | 1 g | 525.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
NUCLEAR-ID® Blue/Green cell viability reagent |
||||||
| Distinguishes between live vs dead cells in a single reagent. | ||||||
| ≥93% (HPLC), Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF | ||||||
| ENZ-53004-C100 | 100 µl | 325.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
NUCLEAR-ID® Blue/Red cell viability reagent (GFP-CERTIFIED®) |
||||||
| Distinguishes between live vs dead cells in a single reagent. | ||||||
| ≥93% (HPLC), Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF | ||||||
| ENZ-53005-C100 | 100 µl | 313.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
NUCLEAR-ID® Red/Green cell viability reagent |
||||||
| Distinguishes between live vs dead cells in a single reagent | ||||||
| ≥93% (HPLC), Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF | ||||||
| ENZ-53006-C100 | 100 µl | 319.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
Pifithrin-α |
||||||
| p53 inhibitor | ||||||
| 63208-82-2, ≥98% (TLC) | Print as PDF | ||||||
| BML-GR325-0005 | 5 mg | 97.00 USD | |
|||
| BML-GR325-0025 | 25 mg | 419.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
Pifithrin-α (cyclic) . hydrobromide |
||||||
| p53 inhibitor | ||||||
| 60477-34-1, ≥95% (HPLC, TLC) | Print as PDF | ||||||
| ALX-270-287-M010 | 10 mg | 215.00 USD | |
|||
| ALX-270-287-M050 | 50 mg | 865.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
p53 activator |
||||||
| p53 activator | ||||||
| ≥97% (HPLC) | Print as PDF | ||||||
| BML-P603-0500 | 0.5 mg | 309.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
