| Alternative Name: | Interleukin-6 receptor, IL6R, MRA |
| |
| Clone: | rhPM-1 (Tocilizumab) |
| |
| Host: | Human |
| |
| Isotype: | IgG1κ |
| |
| Immunogen: | This antibody was prepared by CDR grafting of mouse PM-1 antibody onto a human REI and NEW framework regions to create rhPM-1. |
| |
| UniProt ID: | P08887 |
| |
| Species reactivity: | Human
|
| |
| Specificity: | Recognizes both the membrane bound and soluble forms of human IL-6R. |
| |
| Applications: | ELISA
|
| |
| Purity Detail: | Protein A affinity purified. |
| |
| Formulation: | Liquid. In PBS containing 0.02% Proclin 300. |
| |
| Use/Stability: | Stable at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. |
| |
| Handling: | Avoid freeze/thaw cycles. |
| |
| Shipping: | Blue Ice |
| |
| Short Term Storage: | +4°C |
| |
| Long Term Storage: | -20°C |
| |
| Scientific Background: | The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
