| Alternative Name: | Interleukin-6 receptor, IL6R, MRA |
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| Clone: | rhPM-1 (Tocilizumab) |
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| Host: | Rabbit |
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| Isotype: | IgGκ |
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| Immunogen: | This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions. |
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| UniProt ID: | A0N0L5 |
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| Species reactivity: | Human
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| Specificity: | Recognizes both the membrane bound and soluble forms of human IL-6R. |
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| Applications: | ELISA
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| Purity Detail: | Protein A affinity purified. |
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| Formulation: | Liquid. In PBS containing 0.02% Proclin 300. |
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| Use/Stability: | Stable at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Scientific Background: | The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. |
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| Technical Info/Product Notes: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
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| Regulatory Status: | RUO - Research Use Only |
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