The PATHO-GENE® HPV type 31/33/51 probe is a mixture of biotin-labeled HPV 31, HPV 33 and HPV 51-specific probes in buffered formamide and hybridization enhancers.
Product Details
| Application Notes: | The ENZO PATHO-GENE® HPV type 31/33/51 probe employs a mixture of the HPV 31, HPV 33 and HPV 51-specific probes that detect HPV types that have been associated with either condyloma or cervical intraepithelial neoplasia (CIN) and carcinoma in situ (CIS). The probe mixture is denatured and hybridized to the tissue section fixed and pretreated on the microscope slide. Specific hybridization between the HPV DNA probe and DNA in the specimen is determined by the detection of biotin. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | +4°C |
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| Use/Stability: | Stable for at least one year after receipt when stored as recommended. |
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| Technical Info/Product Notes: | HPV probe can be optimized for polymer detection system using diluent buffer, In situ hybridization buffer for HPV probes (Ready-to Use) (Prod. No. ENZ-33905).
This product or the use of this product is covered by one or more Enzo patents, including, but not limited to the following: U.S. Patent No. 4,994,373; Canadian Patent No. 1,309,672; and patents pending. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
p16 expression in relation to human papillomavirus in liquid-based cervical smears: B. Samama, et al.; Gynecol. Oncol.
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Time course of juvenile onset recurrent respiratory papillomatosis caused by human papillomavirus: M. Hawkes, et al.; Pediatr. Infect. Dis. J.
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p16 expression in relation to human papillomavirus in anogenital lesions: B. Samama, et al.; Hum. Pathol.
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Detection of oncogenic virus genomes and gene products in lung carcinoma: L. Brouchet, et al.; Br. J. Cancer
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Comparison of real-time PCR signal-amplified in situ hybridization and conventional PCR for detection and quantification of human papillomavirus in archival cervical cancer tissue: K. Biedermann, et al.; J. Clin. Microbiol.
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A cardiac allograft recipient with Bowen's disease on a finger and concurrent perianal bowenoid papulosis: M. Ibe, et al.; J. Dermatol.
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DNA copy number changes in cervical adenocarcinoma: A. Dellas, et al.; Clin. Cancer Res.
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Morphologic and biologic studies on ten cases of verrucous carcinoma of the vulva supporting the theory of a discrete clinico-pathologic entity: M. Gualco, et al.; Int. J. Gynecol. Cancer
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Pearly penile papules: still no reason for uneasiness: C.J. Hogewoning, et al.; J. Am. Acad. Dermatol.
49, 50 (2003),
Abstract;
Detection of kappa- and lambda-expressing cells in the endometrium by in situ hybridization: E. Euscher, et al.; Int. J. Gynecol. Pathol.
21, 383 (2002),
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HPV DNA detection by in situ hybridization with catalyzed signal amplification on thin-layer cervical smears: B. Samama, et al.; J. Histochem. Cytochem.
50, 1417 (2002),
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Penile lesions and human papillomavirus in male sexual partners of women with cervical intraepithelial neoplasia: M.C. Bleeker, et al.; J. Am. Acad. Dermatol.
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Primary inverted papilloma of the middle ear and mastoid: C. de Filippis, et al.; Otol. Neurotol.
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Human papillomaviruses 6/11, 16/18 and 31/33/51 are not associated with squamous cell carcinoma of the urinary bladder: P.J. Westenend, et al.; BJU Int.
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Significance of human papillomavirus in sinonasal papillomas: M. Kraft, et al.; J. Laryngol. Otol.
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Squamous papilloma of the esophagus: long-term follow up: S. Mosca, et al.; J. Gastroenterol. Hepatol.
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MIB-1 immunostaining is a beneficial adjunct test for accurate diagnosis of vulvar condyloma acuminatum: E.C. Pirog, et al.; Am. J. Surg. Pathol.
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Abstract;
Use of Probemix and OmniProbe biotinylated cDNA probes for detecting HPV infection in biopsy specimens from the genital tract: I. Zehbe, et al.; J. Clin. Pathol.
46, 437 (1993),
Application(s): in situ hybridization,
Abstract;
Full Text
Human papillomavirus infection and anal carcinoma. Retrospective analysis by in situ hybridization and the polymerase chain reaction: S.R. Zaki, et al.; Am. J. Pathol.
140, 1345 (1992),
Application(s): in situ hybridization,
Abstract;
Full Text
Sensitivity of in situ detection with biotinylated probes of human papilloma virus type 16 DNA in frozen tissue sections of squamous cell carcinomas of the cervix: J.M. Walboomers, et al.; Am. J. Pathol.
131, 587 (1988),
Abstract;
Detection of viral genomes in cultured cells and paraffin-embedded tissue sections using biotin-labeled hybridization probes: D.J. Brigati, et al.; Virology
126, 32 (1983),
Abstract;
Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes: P.R. Langer, et al.; PNAS
78, 6633 (1981),
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