MW: | 65.0 kDa |
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Source: | Produced in E. coli. |
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UniProt ID: | P19838 |
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Formulation: | Liquid. In 50mM HEPES, pH 7.5, 50mM NaCl, 1mM DTT. |
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Purity: | ≥95% (SDS-PAGE) |
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Purity Detail: | Purified by glutathione affinity chromatography. |
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Application Notes: | Uses: For NF-κB pathway studies. Investigate DNA binding of p50. Investigate inhibition by IκBa. GST pull down of interacting partners. |
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Shipping: | Dry Ice |
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Long Term Storage: | -80°C |
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Scientific Background: | NF-κB p50 subunit acts as the DNA binding domain of the major NF-κB heterodimeric complex p50/p65. NF-κB plays an important role in inflammation, autoimmune response, cell proliferation, and apoptosis by regulating the expression of genes involved in these processesNF-κB pathway studies, in conjunction with the p65 subunit. |
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Regulatory Status: | RUO - Research Use Only |
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