| BML-SE460-0010 | 10 µg | 493.00 USD |  |
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| Alternative Name: | ErbB2, Her2, Neu, CD340 |
| MW: | 92 kDa |
| Source: | Produced in insect cells. Active c-erbB2 (aa 679-1255). Produced in a baculovirus expression system. |
| UniProt ID: | P04626 |
| Application Notes: | Useful for kinetic and functional studies, phosphorylation of target substrates, drug screening. |
| Shipping: | Dry Ice |
| Long Term Storage: | -80°C |
| Scientific Background: | c-erbB2 is best known in its role in breast cancer, where it is amplified in approximately 20% of invasive cancers. The humanized monoclonal antibody, trastuzumab, and the small molecule, lapatinib, inhibit c-erbB2. |
| Regulatory Status: | RUO - Research Use Only |
