Replaces Prod. #: ALX-340-020
A major uterine luteolytic prostaglandin. Endogenous agonist of the prostanoid FP receptor (KD=1.0nM). Inhibits differentiation of 3T3-L1 preadipocytes.
Product Details
| Alternative Name: | Dinoprost, 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid, PGF2α |
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| Formula: | C20H34O5 |
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| MW: | 354.5 |
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| CAS: | 551-11-1 |
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| Purity: | ≥99% (TLC) |
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| Appearance: | Low melting white solid or colorless oil. |
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| Solubility: | Soluble in 100% ethanol (50mg/ml). |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Proteostasis regulators restore function of epilepsy-associated GABAA receptors: X. Di, et al.; Cell Chem. Biol.
28, 46 (2021),
Abstract;
Full Text
The mechanism of inhibition of 3T3-L1 preadipocyte differentiation by prostaglandin F2alpha: C.W. Miller, et al.; Endocrinology
137, 5641 (1996),
Abstract;
Cloning and expression of a cDNA for the human prostanoid FP receptor: M. Abramovitz, et al.; J. Biol. Chem.
269, 2632 (1994),
Abstract;
Role of progesterone in regulating uteroovarian venous concentrations of PGF2 alpha and PGE2 during the estrous cycle and early pregnancy in ewes: D.L. Vincent & E.K. Inskeep; Prostaglandins
31, 715 (1986),
Abstract;
