Biosynthesis from dihomo-γ-linolenic acid. A major prostaglandin in semen. Inhibits human platelet aggregation. Effects induced by receptor-mediated elevation of cAMP.
Product Details
Alternative Name: | PGE1 |
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Formula: | C20H34O5 |
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MW: | 354.5 |
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Source: | Synthetic. |
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CAS: | 745-65-3 |
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Purity: | ≥98% (HPLC) |
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Appearance: | White to off-white solid. |
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Solubility: | Soluble in ethanol (50mg/ml) or acetone (10mg/ml). |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Regulation of agonist-induced prostaglandin E1 versus prostaglandin E2 production. A mass analysis: D. Rubin, et al.; J. Biol. Chem.
266, 23618 (1991),
Abstract;
Multiple hormone actions: the rises in cAMP and Ca++ in MDCK-cells treated with glucagon and prostaglandin E1 are independent processes: N. P. Kurstjens, et al.; Biochem. Biophys. Res. Commun.
167, 1162 (1990),
Abstract;
Prostaglandin E1: a review: S. J. Kirtland, et al.; Prostaglandins Leukot. Essent. Fatty Acids
32, 165 (1988),
Abstract;