Inhibits LTC4 biosynthesis by inhibition of glutathione S-transferase (GST). Inhibits 15-hydroxyprostaglandin dehydrogenase.
Product Details
| Alternative Name: | 2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxyacetic acid |
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| MW: | 303.1 |
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| CAS: | 58-54-8 |
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| Purity: | ≥98% |
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| Appearance: | Off-white to white. |
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| Solubility: | Soluble in 100% ethanol (35mg/ml) or DMSO (35mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate: J. H. T. M. Ploemen, et al.; Biochem. Pharmacol.
40, 1631 (1990),
Abstract;
Selective inhibition of leukotriene C4 synthesis in human neutrophils by ethacrynic acid: K. H. Leung, et al.; Biochem. Biophys. Res. Commun.
137, 195 (1986),
Abstract;
