Potent, cell permeable synthetic peptides that irreversibly inhibit activities of each of the caspase-family proteases. YVAD, VDVAD, DEVD, LEVD, WEHD, VEID, IETD, LEHD, and AEVD are the recognition sequences for caspase-1, -2, -3, -4, -5, -6, -8, -9, and -10. VAD is a general caspase inhibitor that inhibits all known caspases. Z-FA-FMK is a negative control for FMK inhibitors.

Product Details

Recommended Dilutions/Conditions:	We recommend using 1,000x dilutions for inhibiting caspase activity in Jurkat cell culture (e.g. add 1µl to 1ml of culture medium). Optimal doses may vary for different cells and culture conditions and must be determined individually.

Contents:	Contains 25µl (2mM) each of the following inhibitors: - Caspase-1 Inhibitor, Z-YVAD-FMK (Prod. No. ALX-260-154), yellow cap - Caspase-2 Inhibitor, Z-VDVAD-FMK (Prod. No. ALX-260-139), orange cap - Caspase-3 Inhibitor, Z-DEVD-FMK (Prod. No. ALX-260-141), red cap - Caspase-4 Inhibitor, Z-LEVD-FMK (Prod. No. ALX-260-142), orange cap - Caspase-5 Inhibitor, Z-WEHD-FMK (Prod. No. ALX-260-140), clear cap - Caspase-6 Inhibitor, Z-VEID-FMK (Prod. No. ALX-260-143), violet cap - Caspase-8 Inhibitor, Z-IETD-FMK (Prod. No. ALX-260-144), green cap - Caspase-9 Inhibitor, Z-LEHD-FMK (Prod. No. ALX-260-145), blue cap - Caspase-10 Inhibitor, Z-AEVD-FMK (Prod. No. ALX-260-146), amber cap - Caspase-13 Inhibitor, Z-LEED-FMK (Prod. No. ALX-260-147), yellow cap - Caspase-Family Inhibitor, Z-VAD-FMK (Prod. No. ALX-260-138), amber cap - FMK Negative Control, Z-FA-FMK (Prod. No. ALX-260-148), clear cap

Formulation:	Liquid. In DMSO.

Shipping:	Blue Ice

Long Term Storage:	-20°C

Regulatory Status:	RUO - Research Use Only

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