Product Details
Alternative Name: | B cell maturation protein, TNFRSF 17, CD269 |
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Clone: | Vicky-2 |
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Host: | Rat |
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Isotype: | IgG2a |
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Immunogen: | Recombinant mouse BCMA extracellular domain (aa 1-46). |
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UniProt ID: | O88472 |
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Source: | Purified from concentrated hybridoma tissue culture supernatant. |
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Species reactivity: | Mouse
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Crossreactivity: | Does not cross-react with human BCMA. |
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Applications: | Flow Cytometry, IP, WB
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Recommended Dilutions/Conditions: | Immunoprecipitation (1:200)
Flow Cytometry (1:1,000)
Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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Purity Detail: | Protein G-affinity purified. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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Use/Stability: | Stable for at least 1 year after receipt when stored at -20°C. |
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Handling: | For long term storage, aliquot and freeze at -20°C. Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Short Term Storage: | +4°C |
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Regulatory Status: | RUO - Research Use Only |
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Western blot analysis of BCMA: Lane 1: MW marker, Lane 2: Mouse BCMA Recombinant Protein.
SDS-PAGE analysis of Prod. No. ALX-804-826: Lane 1: MW marker, Lane 2: 1µg , Lane 3: 2µg BCMA (mouse) monoclonal antibody (Vicky-2), integrity of antibody is shown as both light chain and heavy chain are present.
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Product Literature References
The proteoglycan (heparan sulfate proteoglycan) binding domain of APRIL serves as a platform for ligand multimerization and cross-linking: F.C. Kimberley, et al.; FASEB J.
5, 1584 (2020),
Abstract;
Full Text
APRIL facilitates viral-induced erythroleukemia but is dispensable for T cell immunity and lymphomagenesis: G. Hardenberg, et al.; J. Leukoc. Biol.
84, 380 (2008),
Abstract;
Full Text
General Literature References
TACI and BAFF-R mediate isotype switching in B cells: E. Castigli, et al.; J. Exp. Med.
201, 35 (2005),
Abstract;
B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation: S. Shulga-Morskaya, et al.; J. Immunol.
173, 2331 (2004),
Abstract;
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