Product Details
Alternative Name: | BCL2L1 |
|
Clone: | 1C2 |
|
Host: | Rat |
|
Isotype: | IgG2a κ |
|
Immunogen: | Recombinant mouse Bcl-XL (aa 1-209). |
|
UniProt ID: | Q64373 |
|
Species reactivity: | Human, Mouse
|
|
Applications: | ELISA, Flow Cytometry, IP, WB
|
|
Purity Detail: | Protein G-affinity purified. |
|
Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
|
Handling: | Avoid freeze/thaw cycles. |
|
Shipping: | Blue Ice |
|
Short Term Storage: | +4°C |
|
Long Term Storage: | -20°C |
|
Regulatory Status: | RUO - Research Use Only |
|
Product Literature References
Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak: R.T. Uren, et al.; J. Cell Biol.
177, 277 (2007),
Abstract;
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins: S.N. Willis, et al.; Genes Dev.
19, 1294 (2005),
Abstract;
Full Text