| ALX-804-126-C100 | 100 µg | 372.00 USD |  |
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| Alternative Name: | TRPM-2, SGP-2, CLI, Apolipoprotein J, CLU, APO-J |
| Clone: | CLI-9 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | Purified human clusterin (TRPM-2). |
| UniProt ID: | P10909 |
| Source: | Purified from hybridoma tissue culture supernatant. |
| Species reactivity: | Human |
| Applications: | ICC, IHC (FS), IHC (PS), IP, WB |
| Recommended Dilutions/Conditions: | Western Blot (1:2,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Use/Stability: | Stable for at least 6 months after receipt when stored at +4°C undiluted. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | Clusterin (SGP-2/sulfated glycoprotein-2; CLI; Apolipoprotein J (Apo J); TRPM-2) is the first identified extracellular mammalian chaperone and appears to be implicated in such diverse processes as sperm maturation, regulation of complement activation, programmed cell death, tissue remodelling and lipid transport. Increases in clusterin mRNA and protein have been consistently detected in apoptotic cell death paradigms, establishing clusterin gene expression as a prominent marker of apoptotic cell loss. A dual role has been shown for clusterin in that cells can be protected from damage and dead cells can be more easily removed after some types of cellular damage. |
| Regulatory Status: | RUO - Research Use Only |
