Product Details
| Alternative Name: | Vascular endothelial cadherin, Cadherin-5, CD144, 7B4 antigen |
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| Clone: | BV6 |
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| Host: | Mouse |
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| Isotype: | IgG2a |
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| Immunogen: | Human endothelial cells. |
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| UniProt ID: | P33151 |
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| Species reactivity: | Human
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| Crossreactivity: | Does not cross-react with other species. |
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| Applications: | ELISA, Flow Cytometry, ICC, IHC (FS), IP, WB
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| Recommended Dilutions/Conditions: | Immunocytochemistry (fluorescence and peroxidase staining)
Western Blot (non-reducing)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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| Application Notes: | Detects a band of ~130-140kDa by Western blot. |
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| Purity Detail: | Affinity purified. |
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| Formulation: | Liquid. In PBS containing 1mg/ml BSA and 0.02% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
RhoGEF17-An Essential Regulator of Endothelial Cell Death and Growth: P. Weber, et al.; Cells
10, 741 (2021),
Abstract;
Endothelial Cell-Targeted Deletion of PPARγ Blocks Rosiglitazone-Induced Plasma Volume Expansion and Vascular Remodeling in Adipose Tissue: TE. Akiyama, et al.; J. Pharmacol. Exp. Ther.
368, 514 (2019),
Abstract;
Developmental SMAD6 loss leads to blood vessel hemorrhage and disrupted endothelial cell junctions: LA. Wylie, et al.; Dev. Biol.
442, 199 (2018),
Abstract;
EPAC1 promotes adaptive responses in human arterial endothelial cells subjected to low levels of laminar fluid shear stress: Implications in flow-related endothelial dysfunction: S.N. Rampersad, et al.; Cell. Signal.
28, 606 (2016),
Application(s): Immunofluorescence,
Abstract;
p120-Catenin regulates clathrin-dependent endocytosis of VE-cadherin: K. Xiao, et al.; Mol. Biol. Cell
16, 5141 (2005),
Abstract;
Full Text
Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells: K. Xiao, et al.; J. Cell Biol.
163, 535 (2003),
Abstract;
Full Text
VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells: P. Salven, et al.; Blood
101, 168 (2003),
Abstract;
Full Text
Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability: M. Corada, et al.; Blood
97, 1679 (2001),
Abstract;
Full Text
Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization: T. Murohara, et al.; J. Clin. Invest.
105, 1527 (2000),
Abstract;
Full Text
Differential localization of VE- and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization: P. Navarro, et al.; J. Cell Biol.
140, 1475 (1998),
Abstract;
Full Text
Inhibition of cultured cell growth by vascular endothelial cadherin (cadherin-5/VE-cadherin): L. Caveda, et al.; J. Clin. Invest.
98, 886 (1996),
Abstract;
Full Text
Catenin-dependent and -independent functions of vascular endothelial cadherin: P. Navarro, et al.; J. Biol. Chem.
270, 30965 (1995),
Abstract;
Full Text
Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin: F. Breviario, et al.; Arterioscler. Thromb. Vasc. Biol.
15, 1229 (1995),
Abstract;
