Selective ligand for human or mouse Toll-like receptor 7 (TLR7). Induces the activation of NF-κB in HEK 293 cells expressing TLR7. At high concentrations (3µg/ml) slightly activates TLR8. More active than Imiquimod (Prod. No. ALX-420-039).
Product Details
| Alternative Name: | 1-(4-Amino-2-ethylaminomethylimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol |
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| Formula: | C17H23N5O |
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| MW: | 313.4 |
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| Purity: | ≥98% (HPLC (UV)) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in DMSO (>40mg/ml), dioxane (7mg/ml), methanol (>40mg/ml) or acetonitrile (2mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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