Potent activator of p300 HAT (histone acetyltransferase), but not of PCAF (p300/CBP-associated factor) HAT activities.
Product Details
| Alternative Name: | N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide |
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| Formula: | C31H43ClF3NO2 |
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| MW: | 554.1 |
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| CAS: | 586976-24-1 |
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| Purity: | ≥97% (TLC) |
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| Appearance: | White to off-white crystalline solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy: K. Mantelingu, et al.; J. Phys. Chem. B.
111, 4527 (2007),
Abstract;
General Literature References
Small molecule modulators of histone acetyltransferase p300: K. Balasubramanyam, et al.; J. Biol. Chem.
278, 19134 (2003),
Abstract;
