Glycopeptide antibiotic. Interferes with cell wall synthesis. Effective against Gram-positive bacteria.
Product Details
Formula: | C66H75Cl2N9O24 . HCl |
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MW: | 1449.3 . 36.5 |
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Source: | Isolated from Streptomyces lysosup. |
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CAS: | 1404-93-9 |
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MI: | 14: 9929 |
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RTECS: | YW4380000 |
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Appearance: | White to light brown powder. |
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Activity: | Potency is >900µg/mg (on dry basis). |
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Solubility: | Soluble in water (50mg/ml). |
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Shipping: | Ambient Temperature |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Hydrophobic interactions affect hydrogen bond strengths in complexes between peptides and vancomycin or ristocetin: M.P. Williamson & D.H. Williams; Eur. J. Biochem.
138, 345 (1984),
Abstract;
Structure of vancomycin and its complex with acetyl-D-alanyl-D-alanine: G.M. Sheldrick, et al.; Nature
271, 223 (1978),
Abstract;
Intravitreal injection of vancomycin in experimental staphylococcal endophthalmitis: P. Homer, et al.; Acta Ophthalmol. (Copenh)
53, 311 (1975),
Abstract;