Cation ionophore with high selectivity for ammonium and potassium. Immunosuppressive agent.
Product Details
| Alternative Name: | Antibiotic AKD 1D, Antibiotic S 3466B |
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| Formula: | C43H70O12 |
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| MW: | 779.0 |
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| Source: | Isolated from Streptomyces sp. MST-AS5448. |
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| CAS: | 7561-71-9 |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | Colorless film. |
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| Solubility: | Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Immunosuppressive effects of polynactins (tetranactin, trinactin and dinactin) on experimental autoimmune uveoretinitis in rats: Y. Tanouchi and H. Shichi; Jpn. J. Ophthalmol.
31, 218 (1987),
Abstract;
Antibiotics as tools for metabolic studies. VI. Damped oscillatory swelling of mitochondria induced by nonactin, monactin, dinactin, and trinactin: S. N. Graven, et al.; Biochemistry
5, 1735 (1966),
Abstract;
The in Vitro Activity of Nonactin and Its Homologs: Monactin, Dinactin and Trinactin: E. Meyers, et al.; J. Antibiot. (Tokyo)
18, 128 (1965),
Abstract;
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