Antibiotic. Fungal toxin. Inhibits glucose transport, actin polymerisation and blocks the formation of microtubuli. Inhibits cell division. Inhibits HIV-1 protease.
Product Details
Formula: | C29H35NO5 |
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MW: | 477.6 |
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Source: | Isolated from Drechslera dematoidea. |
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CAS: | 14110-64-6 |
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MI: | 14: 2790 |
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Purity: | ≥98% (HPLC, TLC) |
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Appearance: | White to off-white powder. |
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Solubility: | Soluble in acetone, DMSO or 100% ethanol. |
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Shipping: | Ambient Temperature |
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Long Term Storage: | -20°C |
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Handling: | Protect from light. |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Effect of cytochalasin A on apical growth, actin cytoskeleton organization and enzyme secretion in Aspergillus nidulans: S. Torralba, et al.; Microbiology
144 (Pt 1), 45 (1998),
Abstract;
L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease. III. Biological activity: R.B. Lingham, et al.; J. Antibiot.
45, 686 (1992),
Abstract;
Cytochalasin A inhibits B-lymphocyte capping and activation by antigens: G. Teti, et al.; Immunol. Lett.
3, 151 (1981),
Abstract;
The action of cytochalasin A on the in vitro polymerization of brain tubulin and muscle G-actin: R.H. Himes & L.L. Houston; J. Supramol. Struct.
5, 81 (1976),
Abstract;