Antibiotic which suppresses nitric oxide (NO) toxicity in pancreatic islet cells. Inhibits protein synthesis by inhibition of elongation factor G at the level of the ribosome.
Product Details
| Formula: | C31H47O6 . Na |
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| MW: | 515.7 . 23.0 |
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| CAS: | 751-94-0 |
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| MI: | 14: 4317 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in water (50mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Dumb and dumber--the potential waste of a useful antistaphylococcal agent: emerging fusidic acid resistance in Staphylococcus aureus: B.P. Howden & M.L. Grayson; Clin. Infect. Dis.
42, 394 (2006), Review,
Abstract;
Fusidic acid in vitro activity: P. Collignon and J. Turnidge; Int. J. Antimicrob. Agents
12, S45 (1999), Review,
Abstract;
Fusidic acid non-antibacterial activity: K. Christiansen; Int J Antimicrob Agents
12, S73 (1999), Review,
Abstract;
Fusidic acid suppresses nitric oxide toxicity in pancreatic islet cells: V. Burkart, et al.; Biochem. Pharmacol.
48, 1379 (1994),
Abstract;
Mechanism of protein synthesis inhibition by fusidic acid and related antibiotics: N. Tanaka, et al.; BBRC
30, 278 (1968),
Abstract;
On the Mode of Action of Fusidic Acid: C.L. Harvey, et al.; Biochemistry
5, 3320 (1966),
Abstract;
Fusidic acid: a new antibiotic: W.O. Godtfredsen, et al.; Nature
193, 987 (1962),
Abstract;
