Inducer of glutathione S-transferases and inhibitor of chemically induced carcinogenesis. Mosquitocidal, nematicidal and antifungal. Was shown to inhibit cyclooxygenase-1 and -2 (COX-1 and COX-2) as well as topoisomerase I and topoisomerase II.
Product Details
| Alternative Name: | 3-Butyl-3a,4,5,6-tetrahydro-1(3H)-isobenzofuranone |
| |
| Formula: | C12H18O2 |
| |
| MW: | 194.1 |
| |
| Source: | Isolated from Apium graveolens L. |
| |
| CAS: | 6415-59-4 |
| |
| Purity: | ≥98% (UHPLC) |
| |
| Appearance: | White to off-white solid. |
| |
| Solubility: | Soluble in 100% ethanol or ethyl acetate. |
| |
| Shipping: | Blue Ice |
| |
| Long Term Storage: | -20°C |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
Antioxidant, cyclooxygenase and topoisomerase inhibitory compounds from Apium graveolens Linn. seeds: R.A. Momin & M.G. Nair; Phytomedicine
9, 312 (2002),
Abstract;
Mosquitocidal, nematicidal, and antifungal compounds from Apium graveolens L. seeds: R.A. Momin & M.G. Nair; J. Agric. Food Chem.
49, 142 (2001),
Abstract;
Sedanolide, a natural phthalide from celery seed oil: effect on hydrogen peroxide and tert-butyl hydroperoxide-induced toxicity in HepG2 and CaCo-2 human cell lines: J.A. Woods, et al.; In Vitr. Mol. Toxicol.
14, 233 (2001),
Abstract;
Chemoprevention of benzo[a]pyrene-induced forestomach cancer in mice by natural phthalides from celery seed oil: G.-Q. Zheng, et al.; Nutr. Cancer
19, 77 (1993),
Abstract;
