Potent inhibitor of insulin-like growth factor I receptor (IGF-IR) signalling and breast cancer cell growth in culture and in vivo.
Product Details
| Alternative Name: | IGF-IR Inhibitor, N-(5-Chloro-2-methoxyphenyl)-N’-(2-methyl-4-quinolinyl)urea |
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| Formula: | C18H16ClN3O2 |
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| MW: | 341.8 |
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| CAS: | 196868-63-0 |
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| Purity: | ≥98% (HPLC (UV)) |
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| Appearance: | Off-white solid. |
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| Solubility: | Soluble in DMSO (10mg/ml) or methanol (7mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth: K.L. Gable, et al.; Mol. Cancer Ther.
5, 1079 (2006),
Abstract;
