| ADI-CSA-506-E | 100 µg | 485.00 USD |  |
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| Alternative Name: | LY96, Lymphocyte antigen 96, ESOP-1 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the middle of human MD-2. |
| UniProt ID: | Q9Y6Y9 |
| Gene/Protein Identifier: | NP_056179 (RefSeq) |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | IHC, WB |
| Recommended Dilutions/Conditions: | Immunohistochemistry (2µg/ml) Western Blot (0.5-2.0µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Ion exchange purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs recognize different pathogen-associated molecular patterns, thereby linking the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. |
| Regulatory Status: | RUO - Research Use Only |
