| ADI-AAP-460-E | 100 µg | 481.00 USD |  |
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| Alternative Name: | RIP2, CARDIAK, CARD-containing interleukin-1β converting enzyme associated kinase, RIPK2, Receptor-interacting serine/threonine protein kinase 2, Receptor-interacting protein 2 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the N-terminus of human RICK. |
| UniProt ID: | O43353 |
| GenBank ID: | AF027706 |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | ICC, IP, WB |
| Recommended Dilutions/Conditions: | Immunocytochemistry (10µg/ml) Western Blot (0.5-1.0µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | The RICK (Receptor-interacting serine/threonine protein kinase 2) protein, also known as RIP-like interacting CLARP kinase, and CARD-containing ICE associated kinase, contains an N-terminal kinase domain and a C-terminal CARD domain. Overexpression of RICK results in the activation of NF-κB pathway and also induces apoptosis. RICK represents a kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1beta. |
| Regulatory Status: | RUO - Research Use Only |
