| ADI-AAM-141-E | 100 µg | 375.00 USD |  |
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| Alternative Name: | BH3 interacting domain death agonist |
| Clone: | 5C9 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | Synthetic peptide corresponding to a portion of human BID. |
| UniProt ID: | P55957 |
| Species reactivity: | Human |
| Applications: | WB |
| Recommended Dilutions/Conditions: | Western Blot (1-5µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~24kDa by Western blot. |
| Purity Detail: | Protein A affinity purified. |
| Formulation: | Liquid. In PBS containing 50% glycerol. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | BID is an approximately 22 kDa protein belonging to the Bcl-2 family. BID is a cytosolic protein that is cleaved by caspase-8 in response to death receptor stimulation. Proteolytic cleavage of BID results in the formation of a 15 kDa fragment, referred to as tBID. tBID migrates to the mitochondria where it aids in the release of cytochrome c and the subsequent activation of the apoptosome. tBID serves as a link between death receptor dependent and mitochondrial mediated apoptosis. |
| Regulatory Status: | RUO - Research Use Only |
