| ADI-AAM-140-E | 100 µg | 374.00 USD |  |
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| Alternative Name: | BCL2L4, BCL2-associated X protein |
| Clone: | 4F11 |
| Host: | Mouse |
| Isotype: | IgG2b |
| Immunogen: | Recombinant human Bax. |
| UniProt ID: | Q07812 |
| Species reactivity: | Human, Rat |
| Applications: | IHC, IP, WB |
| Recommended Dilutions/Conditions: | Immunohistochemistry (10µg/ml) Immunoprecipitation (5-10µg/ml) Western Blot (0.1-1.0µg/ml colorimetric, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~22kDa by Western blot. |
| Purity Detail: | Protein A affinity purified. |
| Formulation: | Lyophilized. In PBS, pH 7.2, containing 1% sucrose. Reconstitute with 100μL of distilled water. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | Bax is an appromimately 22 kDa pro-apoptotic protein belonging to the Bcl-2 family of proteins, which are characterized by the presence of at least one Bcl-2 homology (BH) domains. Bax normally resides in the cytoplasm, but following an apoptotic stimuli, Bax undergoes a conformational change and translocates to mitochondrial membranes where it inserts and mediates the release of cytochrome c. This activates caspase-3 and perpetuates the apoptotic cascade. |
| Regulatory Status: | RUO - Research Use Only |
Goat anti-mouse IgG F(ab')2, polyclonal antibody (HRP conjugate) |
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| ELISA, IHC, WB | Print as PDF | ||||||
| ADI-SAB-100-J | 1 ml | 154.00 USD | |
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Goat anti-mouse IgG, polyclonal antibody (AP conjugate) |
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| ELISA, WB | Print as PDF | ||||||
| ADI-SAB-101-J | 1 ml | 175.00 USD | |
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