| ADI-AAM-080-E | 100 µg | 428.00 USD |  |
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| Alternative Name: | BCL2L1 |
| Clone: | 2H12 |
| Host: | Mouse |
| Isotype: | IgG2a |
| Immunogen: | Synthetic peptide corresponding to the sequence near the N-terminus of human Bcl-xL. |
| UniProt ID: | Q07817 |
| Gene/Protein Identifier: | B47537 (PIR) |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | WB |
| Recommended Dilutions/Conditions: | Western Blot (1-5µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~28kDa by Western blot. |
| Purity Detail: | Purified by protein A/G chromatography. |
| Formulation: | Liquid. In PBS. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | The Bcl-2 family of proteins regulate the intrinsic apoptotic pathway and are characterized by the sharing of at least one of four conserved Bcl-2 Homology (BH) domains. Bcl-2 family members function as either pro- or anti-apoptotic factors, and are generally categorized into three groups based on structural homology and function. Bcl-2-like proteins (Bcl-2, Bcl-xL, Bcl-w, A1, and Mcl-1) are pro-survival. Pro-apoptotic members can be sub-divided into two groups: the multi-BH domain group, including Bax, Bak, and Bok; and the more numerous and diverse BH3-only group, which includes Bim, Bad, and Bid. |
| Regulatory Status: | RUO - Research Use Only |
Goat anti-mouse IgG F(ab')2, polyclonal antibody (HRP conjugate) |
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| ELISA, IHC, WB | Print as PDF | ||||||
| ADI-SAB-100-J | 1 ml | 154.00 USD | |
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