Alternative Name: | BlySR3, TNFRSF 13C, CD268 |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human BAFF receptor. |
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UniProt ID: | Q96RJ3 |
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Species reactivity: | Human, Mouse, Rat
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Applications: | IHC, WB
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Recommended Dilutions/Conditions: | Immunohistochemistry (5µg/ml) Western Blot (2-5µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Peptide affinity purified. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | BAFF, or B-cell Activating Factor, is a member of the TNF superfamily also known as BLyS (B Lymphocyte Stimulator), TALL-1 (TNF- and ApoLrelated Leukocyte-expressed Ligand), and THANK (TNF Homologue that Activate Apoptosis, NF-κB and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B-cell activator since it induced B-cell proliferation and immunoglobulin secretion. Three receptors for BAFF were identified and designated TACI, BCMA, and BAFF-R. BAFF and its receptors are essential for B-cell development, survival, and humoral immune responses. |
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Regulatory Status: | RUO - Research Use Only |
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