This oxygen-sensitive phosphorescent probe can be used to assess O2 consumption by cultured cells, isolated mitochondria, microorganisms, tissues, and enzymes.
Detect Mitochondrial Dysfunction Within Minutes of Treatment
Assessment of mitochondrial function with MITO-ID® Extracellular O2 Sensor Kit (A) or traditional ATP assay (B) following treatment with mitochondrial inhibitors (Oligomycin, Rotenone, Antimycin), uncoupling agent (FCCP), or control (DMSO). Results illustrate that drug-induced mitochondrial dysfunction is evident immediately post-treatment (A) despite varying levels of viability @ 24 hours by ATP assay (B).
This pH-sensitive phosphorescent probe can be used to monitor cellular acid extrusion, the result of increased glycolytic flux associated with mitotoxicity.
Efficiently Monitor Glycolytic Activity
Acidification profiles of HepG2 cells treated with glucose transport inhibitors (2DG, Oxamate) or mitochondrial inhibitor (Antimycin) relative to control.
A real-time mitochondrial membrane potential assay with superior sensitivity
Detect MMP Perturbations with 10X More Sensitivity than JC-1
Dual-emission Dye Monitors Energetic Status
MITO-ID® Membrane potential cytotoxicity kit |
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| A Real-time Mitochondrial membrane Potential Assay with Superior Sensitivity | ||||||
| HTS, Microplate | Print as PDF | ||||||
| ENZ-51019-KP002 | 1 Kit | 321.00 USD |  |
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| Do you need bulk/larger quantities? | ||||||
MITO-ID® Membrane potential detection kit |
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| The only assay that monitors energetic status using a simple mix-and-read, no-wash protocol | ||||||
| Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS | Print as PDF | ||||||
| ENZ-51018-0025 | 25 tests | 204.00 USD | |
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| ENZ-51018-K100 | 100 tests | 565.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
