Inflammation is a beneficial host response that protects tissues affected by foreign pathogens or physical injury. When left unchecked, inflammation can cease to be a beneficial event and contribute to the pathogenesis of numerous diseases which include rheumatoid arthritis, chronic bronchitis, emphysema, asthma, psoriasis, cancer, and colitis.
Molecules in the arachidonic acid enzyme cascade play a number of important biological roles, both normal and pathological. The derivatives of arachidonic acid are known as eicosanoids, a group of biologically active oxygenated unsaturated fatty acids. They include prostaglandins, thromboxanes, leukotrienes, hydroxyeicosatetraenoic acids (HETEs), and lipoxins. Eicosanoids have been shown to enhance, as well as attenuate inflammation and have also been linked to carcinogenesis. Enzo Life Sciences offers a wide selection of high sensitivity ELISA kits for detection of eicosanoids, as well as small molecules, antibodies and a bioactive lipid library for studying the role of eicosanoids in inflammation and immunity.
Enzo is a trusted manufacturer of ELISA kits, antibodies and high-purity bioactive lipids and enzymes for the analysis of PGE2 and other prostaglandins.