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Innovative Products to Analyze Immunological Disorders

  • TLRGRADE® LPS & Lipid A Reagents
  • Worry-Free Antibodies

  • Native Bacterial and Viral Antigens
  • Factors for Modulating the Host Response
  • Detect and Identify Viral Infection

Tip The Balance In Your Favor

Comprehensive Tools for Interpreting Immunological Responses

Maintaining the proper balance between immune activation and suppression is critical for physiological functioning of the innate and adaptive immune system. Disruption of this equilibrium leads to immunological disorders including autoimmune diseases, hypersensitivities, and immune deficiency. Enzo Life Sciences provides a comprehensive portfolio of products to detect and modulate the complex processes of immunological disease.


High Purity Ligands & Antibodies for Infectious Disease

Toll-like Receptors

Providing the purest ligands for recognition by pattern recognition receptors.


TLRGRADE® LPS & Lipid A Reagents

  • Ultrapure (≥99.9%)
  • Sterile, ready-to-use liquid formulation
  • No hazardous handling

TLRgrade LPS & Lipid A Reagents

Worry-Free Antibodies

Enzo offers over 50 TLR antibodies validated for flow cytometry and microscopy applications.

TLR antibodies

Fluorescent Dyes for Visualizing Cellular Responses

  • No-transfection and quantitative approach for monitoring autophagy in live cells
  • Validated under a wide range of conditions and with small molecule modulators known to influence autophagy pathways
  • Stringently manufactured to control and eliminate non-specific assay artifacts
  • Distinguishes between different reactive species such as hydrogen peroxide, peroxynitrite and hydroxyl radicals
  • High sensitivity, specificity, and accuracy for live cell studies
  • Complete set of reagents, including ROS inducers and scavengers

Tools For Vaccine Development

Native Bacterial and Viral Antigens

Optimized Expression Systems Deliver Superior Antigenicity
We offer a broad range of native state bacterial and viral antigens for vaccine research. Purified native protein production in the latest mammalian expression systems ensure that the resultant antigens are expressed to a high level, are in their native folded state, and possess all relevant post-translational modifications.

  • High Purity
  • Reproducible scale-up for bulk quantities
  • Lyophilized format for extended shelf-life

Native Bacterial and Viral Antigens

Highly Virulent Bacterial Toxins

B. pertussis
C. difficile
C. diphtheria
C. trachomatis
M. pneumonia
N. gonorrhoeae
T. vaginalis
V. cholera


Viral Agent Probes

Virus Detection Probes for use in a variety of hybridization techniques, including in situ hybridization at low concentrations (50-100 ng/mL). Biotinylated probes have been shown to hybridize to homologous DNA at the same rate and to the same extent as non-biotinylated probes.

Native Bacterial and Viral Antigens

Factors for Modulating the Host Response

Superior Performance From Carefully Engineered TNF Superfamily Ligands

MEGACD40L® (soluble) (human), (recombinant)

  • Highly active MEGACD40L® oligomer mimics in vivo membrane-assisted CD40L aggregation and stimulation without the need for enhancers
  • High purity with low endotoxin levels
  • Experienced manufacturing results in consistent and dependable lot-to-lot performance
  • Optimized formulation for improved stability and enhanced activity

Engineered TNF Superfamily Ligands

Enhance Immune Activation with MEGACD40L® Protein

B cell lymphocyte activation by various CD40L constructs. PBMCs were treated for 48 hrs in media containing serially diluted MEGACD40L, CD40L + 2ug/mL Enhancer, or CD40L. Cells were dual-stained with α-human CD19–PE and α -human CD86–APC and analyzed by flow cytometry. Data are presented as the percent of CD19+ B cells that co-stain as CD86+.


Quantify Biomarkers Of Inflammation With ELISAs

Detect Mediators of Acute and Chronic Inflammation

IL-6 (human), High Sensitivity ELISA Kit

  • Most-sensitive (0.057 pg/mL) colorimetric kit for IL-6 quantification
  • Easy-to-use liquid colorcoded reagents reduce errors
  • Rapid quantitative results in 3 hours
  • High-throughput immunoassay measures up to 40 samples in duplicate per 96-well kit


Histamine ELISA Kit

  • Highly sensitive measurement, detecting as little as 0.068 ng/mL
  • Unique assay which does not require an additional acylation step
  • Rapid results in 2.5 hours for up to 40 samples in duplicate


  • Ultrasensitive measurement of LTB4, detecting as little as 5.63 pg/ml
  • Broad dynamic range suitable for a large variety of samples
  • High throughput format with results in 4 hours for up to 39 samples in duplicate

Cytokine & Eicosanoid

Cytokines are secreted signaling molecules that mediate and regulate immunity, inflammation and many developmental processes during embryogenesis. Cytokines can have pleiotropic, overlapping, and sometimes contradictory functions, and also play an important role in angiogenesis  and cancer. Eicosanoids are a group of biologically active oxygenated unsaturated fatty acids derived from arachidonic acid by the action of cyclooxygenases, lipoxygenases, and cytochrome P450 mono-oxygenases. The eicosanoid family includes prostaglandins, thromboxanes, leukotrienes, hydroxyeicosatetraenoic acids (HETEs), and lipoxins. Eicosanoids have been shown to enhance, as well as attenuate inflammation and have also been linked to carcinogenesis.

Enzo’s portfolio of ELISA kits for cytokines and eicosanoids features:

  • Over 100 sensitive ELISAs for quantifying cytokines and eicosanoids
  • Over 20 years of ELISA development and manufacturing experience
  • Widely cited in peer-reviewed publications
  • Low cost-per-test, high-throughput, multi-plate pack sizes available
  • Time-saving, easy-to-use kits with results in less than 3 hours


Cytokine ELISAs

Broad portfolio of sensitive, high-specificity ELISA kits for human and rodent cytokines.

Eicosanoid ELISAs

Widely cited, ultrasensitive eicosanoid ELISA kits built upon over 20 years of small molecule ELISA development and manufacturing expertise.

Prostaglandin Analysis

Enzo is a trusted manufacturer of ELISA kits, antibodies and high-purity bioactive lipids and enzymes for the analysis of PGE2 and other prostaglandins.

C-Reactive Protein

C-Reactive Protein (CRP) is a pentraxin family protein that is widely used as a biomarker for systemic inflammation and tissue injury. Its primary role in innate immunity is to function as an opsonin for pathogens via activation of the complement pathway and through binding to Fc gamma receptors. CRP has been shown to play an important role in a variety of pathological pathways.



  • Sensitive assay detects as little as 12.685 ng/ml in serum and plasma
  • Highly specific with negligible reactivity to other family members
  • Rapid results in just 1.5 hours

Typical standard curve shows broad range of detection


Your Partner in ELISA Services

We test, so you can discover.

Assay Validation | Western Blot Services | ELISA Services

Detect Specific Cells With CD Markers Antibodies

Enzo Life Sciences offers a broad range of antibodies for use in all areas of immunology. Many are validated for use in key applications such as flow cytometry, immunohistochemistry, immunoprecipitation and Western blotting. Every antibody is backed by our Worry-free Antibody Trial Program, allowing you to evaluate any of our antibodies of interest for your specific application or species without risk.

CD Marker T Cells B Cells Dendritic Cells NK Cells Stem Cell
Macrophages Granulocytes Platelets Erythrocytes Endothelial
CD3 Find
CD4 Find Find Find
CD9 Find Find Find Find Find Find Find Find
CD11a Find Find Find Find Find
CD18 Find Find Find Find Find Find Find
CD20 Find Find
CD23 Find Find Find Find Find Find Find
CD26 Find Find Find Find Find
CD31 Find Find Find Find Find Find Find
CD36 Find Find Find Find Find Find
CD38 Find Find Find Find Find Find
CD38 Find Find Find Find Find Find
CD39 Find Find Find Find Find Find Find
CD40 Find Find Find Find Find Find Find Find
CD40L Find
CD41 Find Find Find
CD41a Find Find
CD41b Find Find
CD42 Find Find
CD42 complex Find Find
CD44 Find Find Find Find Find Find Find Find
CD45 Find Find Find Find Find Find Find
CD45RA Find Find Find Find Find Find
CD49b/CD29 Find Find Find Find Find Find Find Find Find Find
CD49f Find Find Find Find Find Find
CD51 Find Find Find
CD54 Find Find Find Find
CD66a Find Find
CD66b Find
CD66c Find Find
CD66e Find
CD68 Find Find Find Find Find Find
CD74 Find Find Find Find Find Find
CD80 Find Find Find Find
CD83 Find Find Find
CD87 Find Find Find Find Find
CD107b Find Find Find
CD123 Find Find Find Find
CD127 Find Find Find
CD163 Find
CD194 Find Find Find Find Find Find
CD205 Find Find Find
CD207 Find
CD208 Find
CD223 Find Find Find
CD243 Find
CD324 (E-cadherin) Find Find Find Find
CD325 Find

Discover over 150 CD Antibodies validated for Flow Cytometry

Monitor Activity Of Therapeutic Compounds

High-throughput Screening for Multidrug Resistance

  • Quantitative measurements of multidrug resistance activity in live cells
  • Simple and reproducible mix-and-read protocol optimized for flow cytometry
  • Two dye formats allows multiplexing

High-throughput Screening for Multidrug Resistance

The Only Assay for Functional Detection of All Three Clinically Relevant ABC Transporter Proteins

Profiling of ABC transporter activity by known inhibitors was assessed in CHO K1 cells using EFLUXX-ID® Green and eFluxx-ID® Gold dyes.


Fighting Cancer with the Immune System

Immuno-oncology, also known as cancer immunotherapy, refers to the use of a person’s own immune system for the treatment of cancer. Research in the field includes:

  • Targeting immune tolerance via co-inhibitory immune checkpoints
  • Enhancing immune responses by costimulatory checkpoint pathways
At Enzo, our diverse scientific and technical expertise has helped us create innovative assays and reagents to help support cancer immunotherapy. We offer a complete set of solutions for Immuno-oncology research including antibodies, ELISA kits and recombinant proteins.


MBL - Mannan-Binding Lectin

MBL (Mannan-Binding Lectin) is a carbohydrate-binding protein produced in the liver and secreted into the blood. The protein plays a key factor in innate immunity, functioning as a player in the complement activation cascade and defending the body against invading microorganisms (bacteria, viruses, protozoa and fungi).

MBL - Mannan-Binding Lectin

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